Primary Aldosteronism and Cardiovascular Events

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Primary Aldosteronism vidence for an Increased Rate of Cardiovascular vents in Patients With Primary Aldosteronism

OBJECTIVES The aim of this report was to show that the rate of cardiovascular events is increased in patients with either subtype of primary aldosteronism (PA). BACKGROUND Primary aldosteronism involves hypertension (HTN), hypokalemia, and low plasma renin. The two major PA subtypes are unilateral aldosterone-producing adenoma (APA) and bilateral adrenal hyperplasia. METHODS During a three-year...

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Is it Possible to Extirpate Cardiovascular Events in Primary Aldosteronism After Surgical Treatment

It is well known that primary aldosteronism (PA) due to aldosterone-producing adenoma (APA) is a surgically curable secondary hypertension. Thus, the differential diagnosis between unilateral hyperaldosteronemia due to APA and bilateral hyperaldosteronemia due to idiopathic hyperaldosteronism (IHA) is crucial to decide surgical indication for treatment in PA patients. Adrenal venous sampling (A...

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Cardiovascular outcomes in patients with primary aldosteronism after treatment.

BACKGROUND Experimental and human studies demonstrate that long-term exposure to elevated aldosterone levels results in cardiac and vascular damage. METHODS We investigated long-term cardiovascular outcomes in patients with primary aldosteronism after surgical or medical treatment. Fifty-four patients with or without evidence of adrenal adenomas were prospectively followed up for a mean of 7....

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[Primary aldosteronism].

Franco Mantero, Gian Paolo Rossi, Enrico Agabiti Rosei Endocrine Unit, Department of Medical and Surgical Sciences, University of Padua, Italy Internal Medicine 4, Department of Clinical and Experimental Medicine, University of Padua, Italy Clinica Medica, Department of Medical and Surgical Sciences, University of Brescia, Italy European Society of Hypertension Scientific Newsletter: Update on ...

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Primary aldosteronism and its variants.

Primary aldosteronism is an adrenal abnormality in which there is an excessive production of aldosterone above that required for electrolyte homeostasis which is not driven by known stimulators of aldosterone secretion, although these may retain some degree of modulatory activity on aldosterone secretion. In the early years following the description of primary aldosteronism, the etiology was as...

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ژورنال

عنوان ژورنال: Hypertension

سال: 2018

ISSN: 0194-911X,1524-4563

DOI: 10.1161/hypertensionaha.117.10405